Medusa

Medusa was a gorgon in Greek mythology whose appearance was so hideous that all who looked upon her turned to stone. She was the youngest of three, and the only mortal sister, her two sisters being Euryale and Stheno. Her consort is Poseidon/Neptune.

Media
Medusa has been featured in the video game Smite

She has also made an appearance as an antagonist in the Percy Jackson series by Rick Riordan